The structure of MP-4 from Mucuna pruriens at 2.22 Å resolution
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چکیده
منابع مشابه
Mucuna pruriens in Parkinson disease
OBJECTIVE To investigate whether Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in all tropical areas worldwide, may be used as alternative source of levodopa for indigent individuals with Parkinson disease (PD) who cannot afford long-term therapy with marketed levodopa preparations. METHODS We investigated efficacy and safety of single-dose intake of MP powder from roas...
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Plants have been used as medicine for the treatment of diseases for thousands of years. These herbal remedies, although natural, can cause some serious damaging effects on the vital organs of the body due to inadequacy in standardization and safety regulations. Mucuna pruriens Linn. belongs to family Fabaceae and is used traditionally in various ailments. The present study reports the acute sys...
متن کاملThe structure of the eukaryotic ribosome at 3.0 Å resolution.
Ribosomes translate genetic information encoded by messenger RNA into proteins. Many aspects of translation and its regulation are specific to eukaryotes, whose ribosomes are much larger and intricate than their bacterial counterparts. We report the crystal structure of the 80S ribosome from the yeast Saccharomyces cerevisiae--including nearly all ribosomal RNA bases and protein side chains as ...
متن کاملLevodopa in Mucuna pruriens and its degradation
Mucuna pruriens is the best known natural source of L-dopa, the gold standard for treatment of Parkinsonism. M. pruriens varieties are protein rich supplements, and are used as food and fodder worldwide. Here, we report L-dopa contents in seeds of fifty six accessions of four M. pruriens varieties, M. pruriens var. pruriens, M. pruriens var. hirsuta, M. pruriens var. utilis and M. pruriens var....
متن کاملNutritional quality and physicochemical properties of Mucuna bean (Mucuna pruriens L.) protein isolates
The potential for mucuna bean protein isolate (MBPI) application as functional ingredient in foods is unknown. In this study nutritional quality and physicochemical properties of MBPI were investigated. Bean samples were processed for L-dopa extraction in distilled water adjusted to pH 3.2 at 60°C for 48hr. MBPI was extracted at pH 9.0 and isoelectrically precipitated at pH 4.5. MBPI from raw a...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section F Structural Biology Communications
سال: 2020
ISSN: 2053-230X
DOI: 10.1107/s2053230x20000199